Menopause defined as the permanent cessation of menses due to loss of ovarian follicular activity1. Determined after 12 consecutive months of amenorrhea1,2. Average age of onset is 51 years old (range 40-58 years)3
Menopausal signs and symptoms:
A woman (≥ 40 years) presents with
References:
Santoro NF. In: Crandall CJ et al. (eds) Menopause Practice: A Clinician’s Guide, 6th edn. 2019.
Jameson JL et al. Harrison’s Principles of Internal Medicine, 20th edn. 2018.
Shifren JL et al. Menopause. 2014;21(10):1038–10621. Monteleone P et al. Nat Rev Endocrinol 2018;14(4):199–215. 2. Thurston RC. In: Crandall CJ et al. (eds) Menopause Practice: A Clinician’s Guide, 6th edn. 2019. 3. English M et al. J Patient Rep Outcomes 2021;5:37.
Portman DJ et al. Menopause 2014;21(10):1063–1068.